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immt-1 MICOS complex subunit MIC60-1 [ Caenorhabditis elegans ]

Gene ID: 180566, updated on 9-Dec-2024

Summary

Official Symbol
immt-1
Official Full Name
MICOS complex subunit MIC60-1
Primary source
WormBase:WBGene00020511
Locus tag
CELE_T14G11.3
See related
AllianceGenome:WB:WBGene00020511
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in cristae formation and response to reactive oxygen species. Located in mitochondrial inner membrane. Part of proton-transporting ATP synthase complex. Orthologous to human IMMT (inner membrane mitochondrial protein). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See immt-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (2682754..2687184, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Membrane-associated protein Neighboring gene TNFR-Cys domain-containing protein Neighboring gene Ig-like domain-containing protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in cristae formation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cristae formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to reactive oxygen species IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of MICOS complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
part_of proton-transporting ATP synthase complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
MICOS complex subunit MIC60-1
NP_508475.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    2682754..2687184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076074.8NP_508475.2  MICOS complex subunit MIC60-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508475.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22505
    Conserved Domains (1) summary
    pfam09731
    Location:64671
    Mitofilin; Mitochondrial inner membrane protein