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flp-18 SVPGVLRF-amide 3 [ Caenorhabditis elegans ]

Gene ID: 180587, updated on 9-Dec-2024

Summary

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Official Symbol
flp-18
Official Full Name
SVPGVLRF-amide 3
Primary source
WormBase:WBGene00001461
Locus tag
CELE_Y48D7A.2
See related
AllianceGenome:WB:WBGene00001461
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable neuropeptide Y receptor binding activity. Involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. Predicted to be located in extracellular space. Is expressed in coelomocyte; head; nervous system; tail; and in male. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See flp-18 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Sequence:
Chromosome: X; NC_003284.9 (3012190..3014286, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene TransThyretin-Related family domain Neighboring gene ncRNA Neighboring gene Aquaporin-9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Simplified method for cell-specific gene expression analysis in Caenorhabditis elegans. Sugi T, et al. Biochem Biophys Res Commun, 2014 Jul 18. PMID 24942876
  2. Isolation and preliminary biological assessment of AADGAPLIRFamide and SVPGVLRFamide from Caenorhabditis elegans. Marks NJ, et al. Biochem Biophys Res Commun, 2001 Sep 7. PMID 11527423
  3. The Brugia malayi neuropeptide receptor-4 is activated by FMRFamide-like peptides and signals via Gαi. Anderson RC, et al. Mol Biochem Parasitol, 2014 Jun. PMID 25038481
  4. Homeostasis in C. elegans sleep is characterized by two behaviorally and genetically distinct mechanisms. Nagy S, et al. Elife, 2014 Dec 4. PMID 25474127, Free PMC Article
  5. Food for thought: a receptor finds its ligand. Potter CJ, et al. Nat Neurosci, 2003 Nov. PMID 14583748

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables neuropeptide Y receptor binding IC
Inferred by Curator
more info
 PubMed 
Process Evidence Code Pubs
involved_in neuropeptide signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of muscle contraction IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sleep IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IC
Inferred by Curator
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IC
Inferred by Curator
more info
 PubMed 

General protein information

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Preferred Names
SVPGVLRF-amide 3
NP_508514.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    3012190..3014286 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076113.9 → NP_508514.2  SVPGVLRF-amide 3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508514.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86MI4, Q9N4V0
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N4V0.2

Gene LinkOut

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