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igcm-2 B-cell receptor CD22-like [ Caenorhabditis elegans ]

Gene ID: 180913, updated on 2-Nov-2024

Summary

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Official Symbol
igcm-2
Official Full Name
B-cell receptor CD22-like
Primary source
WormBase:WBGene00020130
Locus tag
CELE_SSSD1.1
See related
AllianceGenome:WB:WBGene00020130
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cell adhesion molecule binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in membrane. Predicted to be active in cell-cell junction and plasma membrane. Is expressed in gonad; head neurons; hypodermis; and intestine. Orthologous to several human genes including IGSF9 (immunoglobulin superfamily member 9). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See igcm-2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
19
Sequence:
Chromosome: X; NC_003284.9 (6379372..6391591, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene CHCH domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene LAMP family protein lmp-1 Neighboring gene Ig-like domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolutionary conservation of putative suicidality-related risk genes that produce diminished motivation corrected by clozapine, lithium and antidepressants. Ajayi T, et al. Front Psychiatry, 2024. PMID 38362034, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cell adhesion molecule binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cell-cell junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
B-cell receptor CD22-like
NP_001362087.1
  • Confirmed by transcript evidence
NP_001362088.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    6379372..6391591 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001375052.3 → NP_001362088.1  B-cell receptor CD22-like [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5E4M2E1
    Conserved Domains (4) summary
    smart00410
    Location:195 → 279
    IG_like; Immunoglobulin like
    cd00063
    Location:457 → 529
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam13927
    Location:290 → 352
    Ig_3; Immunoglobulin domain
    cl11960
    Location:105 → 181
    Ig; Immunoglobulin domain

  2. NM_001375051.2 → NP_001362087.1  B-cell receptor CD22-like [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5E4LXP4
    Conserved Domains (4) summary
    smart00410
    Location:214 → 298
    IG_like; Immunoglobulin like
    cd00063
    Location:476 → 548
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam13927
    Location:309 → 371
    Ig_3; Immunoglobulin domain
    cl11960
    Location:124 → 200
    Ig; Immunoglobulin domain
Nucleotide Protein
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