tmbi-4 Transmembrane BAX inhibitor motif-containing protein 4 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: tmbi-4
Official Full Name: Transmembrane BAX inhibitor motif-containing protein 4
Primary source: WormBase:WBGene00006479
Locus tag: CELE_B0563.4
See related: AllianceGenome:WB:WBGene00006479
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable calcium channel activity. Predicted to be involved in endoplasmic reticulum unfolded protein response. Predicted to be active in membrane. Orthologous to human TMBIM4 (transmembrane BAX inhibitor motif containing 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tmbi-4 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 7

Sequence:: Chromosome: X; NC_003284.9 (9150694..9160650)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

B0563.4 (e-PCR)
- UniSTS:320198

B0563.3 (e-PCR)
- UniSTS:318973

B0563.7 (e-PCR)
- UniSTS:318974

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables calcium channel activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in endoplasmic reticulum unfolded protein response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Transmembrane BAX inhibitor motif-containing protein 4

NP_509543.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

9150694..9160650

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_077142.9 → NP_509543.2 Transmembrane BAX inhibitor motif-containing protein 4 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_509543.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q11079, Q11080

Conserved Domains (1) summary

cd10429
Location:43 → 275

GAAP_like; Golgi antiapoptotic protein