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nkb-3 Sodium/potassium-transporting ATPase subunit beta;putative sodium/potassium-transporting ATPase subunit beta-3 [ Caenorhabditis elegans ]

Gene ID: 181494, updated on 2-Nov-2024

Summary

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Official Symbol
nkb-3
Official Full Name
Sodium/potassium-transporting ATPase subunit beta;putative sodium/potassium-transporting ATPase subunit beta-3
Primary source
WormBase:WBGene00010117
Locus tag
CELE_F55F3.3
See related
AllianceGenome:WB:WBGene00010117
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ATPase activator activity. Predicted to be involved in intracellular monoatomic cation homeostasis and monoatomic cation transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to several human genes including ATP1B4 (ATPase Na+/K+ transporting family member beta 4); ATP1B1 (ATPase Na+/K+ transporting subunit beta 1); and ATP1B2 (ATPase Na+/K+ transporting subunit beta 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nkb-3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Sequence:
Chromosome: X; NC_003284.9 (13765359..13770558, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Carboxylic ester hydrolase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Caenorhabditis elegans genomic response to soil bacteria predicts environment-specific genetic effects on life history traits. Coolon JD, et al. PLoS Genet, 2009 Jun. PMID 19503598, Free PMC Article
  2. SAFER, an Analysis Method of Quantitative Proteomic Data, Reveals New Interactors of the C. elegans Autophagic Protein LGG-1. Yi Z, et al. J Proteome Res, 2016 May 6. PMID 26999449
  3. Peroxiredoxin 2 is required for the redox mediated adaptation to exercise. Xia Q, et al. Redox Biol, 2023 Apr. PMID 36791646, Free PMC Article
  4. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
  5. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular potassium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular sodium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion export across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of sodium:potassium-exchanging ATPase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of sodium:potassium-exchanging ATPase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sodium/potassium-transporting ATPase subunit beta;putative sodium/potassium-transporting ATPase subunit beta-3
NP_001294779.1
  • Confirmed by transcript evidence
NP_510300.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    13765359..13770558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001307850.4 → NP_001294779.1  Sodium/potassium-transporting ATPase subunit beta [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294779.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    V6CLW5
    Conserved Domains (1) summary
    pfam00287
    Location:2 → 286
    Na_K-ATPase; Sodium / potassium ATPase beta chain

  2. NM_077899.7 → NP_510300.1  putative sodium/potassium-transporting ATPase subunit beta-3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510300.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XUY5
    Conserved Domains (1) summary
    pfam00287
    Location:24 → 300
    Na_K-ATPase; Sodium / potassium ATPase beta chain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XUY5.1

Gene LinkOut

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