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cytb-5.1 Cytochrome b5 heme-binding domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 181510, updated on 9-Dec-2024

Summary

Official Symbol
cytb-5.1
Official Full Name
Cytochrome b5 heme-binding domain-containing protein
Primary source
WormBase:WBGene00007848
Locus tag
CELE_C31E10.7
See related
AllianceGenome:WB:WBGene00007848
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable heme binding activity. Located in perinuclear region of cytoplasm. Is expressed in intestine. Used to study hematopoietic system disease. Human ortholog(s) of this gene implicated in methemoglobinemia and methemoglobinemia and ambiguous genitalia. Orthologous to human CYB5A (cytochrome b5 type A) and CYB5B (cytochrome b5 type B). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See cytb-5.1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
4
Sequence:
Chromosome: X; NC_003284.9 (14001924..14003080)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene CCDC93 N-terminal domain-containing protein Neighboring gene CCDC93 N-terminal domain-containing protein Neighboring gene TBC1 domain family member 2B Neighboring gene tRNA-Gly Neighboring gene ncRNA Neighboring gene Nematode Specific Peptide family, group A

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables heme binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Cytochrome b5 heme-binding domain-containing protein
NP_510335.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    14001924..14003080
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077934.9NP_510335.2  Cytochrome b5 heme-binding domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510335.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93315
    Conserved Domains (1) summary
    pfam00173
    Location:880
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain