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pkhm-2 PH domain-containing protein;RUN domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 181612, updated on 9-Dec-2024

Summary

Official Symbol
pkhm-2
Official Full Name
PH domain-containing protein;RUN domain-containing protein
Primary source
WormBase:WBGene00011680
Locus tag
CELE_T10B10.3
See related
AllianceGenome:WB:WBGene00011680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable kinesin binding activity. Predicted to be involved in Golgi organization; lysosome localization; and regulation of protein localization. Predicted to be located in lysosome. Predicted to be active in endosome membrane. Is expressed in anterior gonad arm. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See pkhm-2 in Genome Data Viewer
Location:
chromosome: X
Exon count:
9
Sequence:
Chromosome: X; NC_003284.9 (15178096..15181465, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Ion transport domain-containing protein Neighboring gene Peptidase M16 N-terminal domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables kinesin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in lysosome localization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of protein localization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
PH domain-containing protein;RUN domain-containing protein
NP_001408270.1
  • Partially confirmed by transcript evidence
NP_510523.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    15178096..15181465 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078122.6NP_510523.1  RUN domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510523.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22368
    Conserved Domains (2) summary
    smart00233
    Location:515607
    PH; Pleckstrin homology domain
    pfam00169
    Location:515608
    PH; PH domain
  2. NM_001421342.1NP_001408270.1  PH domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S4QCL7