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slc-17.1 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 181777, updated on 9-Dec-2024

Summary

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Official Symbol
slc-17.1
Official Full Name
Major facilitator superfamily (MFS) profile domain-containing protein
Primary source
WormBase:WBGene00022647
Locus tag
CELE_ZK54.1
See related
AllianceGenome:WB:WBGene00022647
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Located in sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in sialuria. Orthologous to human SLC17A5 (solute carrier family 17 member 5). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See slc-17.1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (17460778..17464901, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Myosin regulatory light chain 1 Neighboring gene MFS transporter Neighboring gene Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in sarcoplasmic reticulum HDA PubMed 

General protein information

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Preferred Names
Major facilitator superfamily (MFS) profile domain-containing protein
NP_001041300.1
  • Confirmed by transcript evidence
NP_001041301.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    17460778..17464901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047836.7 → NP_001041301.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041301.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2PJ91
    Conserved Domains (1) summary
    cd17318
    Location:37 → 455
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

  2. NM_001047835.5 → NP_001041300.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041300.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q23514
    Conserved Domains (1) summary
    cd17318
    Location:42 → 460
    MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters
Nucleotide Protein
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