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sup-10 Putative potassium channel regulatory protein sup-10 [ Caenorhabditis elegans ]

Gene ID: 181784, updated on 4-Jan-2025

Summary

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Official Symbol
sup-10
Official Full Name
Putative potassium channel regulatory protein sup-10
Primary source
WormBase:WBGene00006319
Locus tag
CELE_R09G11.1
See related
AllianceGenome:WB:WBGene00006319
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables potassium channel regulator activity. Involved in regulation of muscle contraction and regulation of potassium ion transport. Located in plasma membrane and striated muscle dense body. Is expressed in anal depressor muscle; body wall musculature; head neurons; intestinal muscle; and vulval muscle. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See sup-10 in Genome Data Viewer
Location:
chromosome: X
Exon count:
6
Sequence:
Chromosome: X; NC_003284.9 (17528344..17531985)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene Nuclear hormone receptor family member nhr-1;Nuclear receptor domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of revertants of unc-93(e1500) in Caenorhabditis elegans induced by N-ethyl-N-nitrosourea. De Stasio E, et al. Genetics, 1997 Oct. PMID 9335597, Free PMC Article
  2. A visible allele of the muscle gene sup-10X of C. elegans. Greenwald I, et al. Genetics, 1986 May. PMID 3710144, Free PMC Article
  3. sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans. de la Cruz IP, et al. J Neurosci, 2003 Oct 8. PMID 14534247, Free PMC Article
  4. Functions of the Caenorhabditis elegans regulatory myosin light chain genes mlc-1 and mlc-2. Rushforth AM, et al. Genetics, 1998 Nov. PMID 9799259, Free PMC Article
  5. The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9. de la Cruz IP, et al. PLoS Genet, 2014 Feb. PMID 24586202, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables potassium channel regulator activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of muscle contraction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of potassium ion transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in striated muscle dense body IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Putative potassium channel regulatory protein sup-10
NP_510835.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    17528344..17531985
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078434.7 → NP_510835.1  Putative potassium channel regulatory protein sup-10 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510835.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q17374, Q21879
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q17374.2

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