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mct-2 MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein;Monocarboxylate transporter 14 [ Caenorhabditis elegans ]

Gene ID: 182056, updated on 2-Nov-2024

Summary

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Official Symbol
mct-2
Official Full Name
MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein;Monocarboxylate transporter 14
Primary source
WormBase:WBGene00015273
Locus tag
CELE_C01B4.9
See related
AllianceGenome:WB:WBGene00015273
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human SLC16A4 (solute carrier family 16 member 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mct-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (2483004..2494791, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene Aldose 1-epimerase Neighboring gene Serpentine Receptor, class D (Delta)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The protein tyrosine phosphatase PPH-7 is required for fertility and embryonic development in C. elegans at elevated temperatures. Franziscus CA, et al. FEBS Open Bio, 2024 Mar. PMID 38320757, Free PMC Article
  2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables monocarboxylic acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monocarboxylic acid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein;Monocarboxylate transporter 14
NP_001303711.1
  • Predicted
NP_001303712.1
  • Predicted
NP_001303713.1
  • Predicted
NP_503681.2
  • Predicted

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    2483004..2494791 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071280.2 → NP_503681.2  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503681.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q966D6, Q9UAT3
    Conserved Domains (1) summary
    cd17352
    Location:45 → 519
    MFS_MCT_SLC16; Monocarboxylate transporter (MCT) family of the Major Facilitator Superfamily of transporters

  2. NM_001316782.1 → NP_001303711.1  MFS domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0M7RFF6
    Conserved Domains (1) summary
    cd17352
    Location:1 → 367
    MFS_MCT_SLC16; Monocarboxylate transporter (MCT) family of the Major Facilitator Superfamily of transporters

  3. NM_001316783.1 → NP_001303712.1  Monocarboxylate transporter 14 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0M7RDR8
    Conserved Domains (1) summary
    cl28910
    Location:1 → 178
    MFS; Major Facilitator Superfamily

  4. NM_001316784.1 → NP_001303713.1  MFS domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0M7RE14
    Conserved Domains (1) summary
    cl28910
    Location:1 → 47
    MFS; Major Facilitator Superfamily

RNA

  1. NR_133603.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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