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abu-15 Activated in Blocked Unfolded protein response [ Caenorhabditis elegans ]

Gene ID: 182136, updated on 4-Jan-2025

Summary

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Official Symbol
abu-15
Official Full Name
Activated in Blocked Unfolded protein response
Primary source
WormBase:WBGene00004099
Locus tag
CELE_C03A7.4
See related
AllianceGenome:WB:WBGene00004099
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in endoplasmic reticulum unfolded protein response and pharynx development. Predicted to be active in endoplasmic reticulum membrane. Is expressed in pharyngeal muscle cell. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See abu-15 in Genome Data Viewer
Location:
chromosome: V
Exon count:
2
Sequence:
Chromosome: V; NC_003283.11 (5158602..5159907)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene ncRNA Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene Activated in Blocked Unfolded protein response

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cranberry extract standardized for proanthocyanidins promotes the immune response of Caenorhabditis elegans to Vibrio cholerae through the p38 MAPK pathway and HSF-1. Dinh J, et al. PLoS One, 2014. PMID 25062095, Free PMC Article
  2. Toxicogenomic responses of the model organism Caenorhabditis elegans to gold nanoparticles. Tsyusko OV, et al. Environ Sci Technol, 2012 Apr 3. PMID 22372763
  3. Dynamically-expressed prion-like proteins form a cuticle in the pharynx of Caenorhabditis elegans. George-Raizen JB, et al. Biol Open, 2014 Oct 31. PMID 25361578, Free PMC Article
  4. Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes. Sun J, et al. Science, 2011 May 6. PMID 21474712, Free PMC Article
  5. Unfolded protein response genes regulated by CED-1 are required for Caenorhabditis elegans innate immunity. Haskins KA, et al. Dev Cell, 2008 Jul. PMID 18606143, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum unfolded protein response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in pharynx development IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Activated in Blocked Unfolded protein response
NP_504382.1
  • Product from WormBase gene class abu;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    5158602..5159907
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071981.6 → NP_504382.1  Activated in Blocked Unfolded protein response [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504382.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16500
Nucleotide Protein
Heading Accession and Version

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