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C07B5.4 PH domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 182361, updated on 2-Nov-2024

Summary

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Official Symbol
C07B5.4
Official Full Name
PH domain-containing protein
Primary source
WormBase:WBGene00007409
Locus tag
CELE_C07B5.4
See related
AllianceGenome:WB:WBGene00007409
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in actomyosin contractile ring assembly; mitotic cytokinesis; and septin ring organization. Predicted to be active in actomyosin contractile ring. Orthologous to several human genes including RTKN2 (rhotekin 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See C07B5.4 in Genome Data Viewer
Location:
chromosome: X
Exon count:
13
Sequence:
Chromosome: X; NC_003284.9 (9529660..9536631)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene FLYWCH-type domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in actomyosin contractile ring assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic cytokinesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in septin ring organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actomyosin contractile ring IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
PH domain-containing protein
NP_001024370.1
  • Confirmed by transcript evidence
NP_001024371.2
  • Confirmed by transcript evidence
NP_001382743.1
  • Confirmed by transcript evidence
NP_001382744.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    9529660..9536631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001029199.7 → NP_001024370.1  PH domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024370.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q17777
    Conserved Domains (2) summary
    pfam00169
    Location:241 → 340
    PH; PH domain
    pfam08174
    Location:59 → 201
    Anillin; Cell division protein anillin

  2. NM_001395789.1 → NP_001382743.1  PH domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8D9IA70
    Conserved Domains (1) summary
    cl17171
    Location:265 → 339
    PH-like; Pleckstrin homology-like domain

  3. NM_001029200.7 → NP_001024371.2  PH domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001024371.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5WRQ4
    Conserved Domains (2) summary
    pfam00169
    Location:196 → 295
    PH; PH domain
    pfam08174
    Location:14 → 156
    Anillin; Cell division protein anillin

  4. NM_001395790.1 → NP_001382744.1  PH domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8D9I6W5
    Conserved Domains (1) summary
    cl17171
    Location:220 → 294
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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