U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

symk-1 DUF3453 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 182490, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
symk-1
Official Full Name
DUF3453 domain-containing protein
Primary source
WormBase:WBGene00017797
Locus tag
CELE_F25G6.2
See related
AllianceGenome:WB:WBGene00017797
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mRNA processing. Predicted to be located in nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human SYMPK (symplekin scaffold protein). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See symk-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (8570311..8581745)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Acetylcholine receptor subunit alpha-type acr-16 Neighboring gene Signal recognition particle 14 kDa protein Neighboring gene Signal recognition particle 14 kDa protein Neighboring gene MULE transposase domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Regulation of the hypertonic stress response by the 3' mRNA cleavage and polyadenylation complex. Urso SJ, et al. Genetics, 2023 May 4. PMID 36972377, Free PMC Article
  2. Caenorhabditis elegans mutant allele identification by whole-genome sequencing. Sarin S, et al. Nat Methods, 2008 Oct. PMID 18677319, Free PMC Article
  3. Lifespan regulation by evolutionarily conserved genes essential for viability. Curran SP, et al. PLoS Genet, 2007 Apr 6. PMID 17411345, Free PMC Article
  4. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
  5. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mRNA cleavage and polyadenylation specificity factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
DUF3453 domain-containing protein
NP_505210.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    8570311..8581745
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072809.7 → NP_505210.2  DUF3453 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505210.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16929
    Conserved Domains (2) summary
    pfam11935
    Location:111 → 347
    DUF3453; Domain of unknown function (DUF3453)
    pfam12295
    Location:889 → 1070
    Symplekin_C; Symplekin tight junction protein C terminal
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.