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flp-21 GLGPRPLRF-amide [ Caenorhabditis elegans ]

Gene ID: 182944, updated on 4-Jan-2025

Summary

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Official Symbol
flp-21
Official Full Name
GLGPRPLRF-amide
Primary source
WormBase:WBGene00001464
Locus tag
CELE_C26F1.10
See related
AllianceGenome:WB:WBGene00001464
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Enables neuropeptide Y receptor binding activity. Involved in feeding behavior; neuropeptide signaling pathway; and sleep. Predicted to be located in extracellular space. Is expressed in several structures, including P6; P7; P9; and nervous system. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See flp-21 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (7793367..7794025)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Cytochrome P450 Neighboring gene Prion-like-(Q/N-rich)-domain-bearing protein Neighboring gene Neuropeptide-Like Protein Neighboring gene UV-stimulated scaffold protein A homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Engineering bacteria to form a biofilm and induce clumping in Caenorhabditis elegans. Dorado-Morales P, et al. ACS Synth Biol, 2014 Dec 19. PMID 24933529
  2. A neuropeptide modulates sensory perception in the entomopathogenic nematode Steinernema carpocapsae. Morris R, et al. PLoS Pathog, 2017 Mar. PMID 28253355, Free PMC Article
  3. Pheromone-based communication influences the production of somatic extracellular vesicles in C. elegans. Szczepańska A, et al. Nat Commun, 2024 Mar 28. PMID 38548742, Free PMC Article
  4. A gene involved in nematode feeding behaviour. Sawarkar R. J Biosci, 2004 Mar. PMID 15295205
  5. NMR analysis of Caenorhabditis elegans FLP-18 neuropeptides: implications for NPR-1 activation. Dossey AT, et al. Biochemistry, 2006 Jun 20. PMID 16768454, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables neuropeptide Y receptor binding IC
Inferred by Curator
more info
 PubMed 
enables neuropeptide Y receptor binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in feeding behavior IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in neuropeptide signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in sleep IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IC
Inferred by Curator
more info
 PubMed 

General protein information

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Preferred Names
GLGPRPLRF-amide
NP_505011.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    7793367..7794025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072610.7 → NP_505011.2  GLGPRPLRF-amide [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_505011.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q18234
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q18234.2

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