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C27C7.5 Galectin [ Caenorhabditis elegans ]

Gene ID: 182958, updated on 4-Jan-2025

Summary

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Official Symbol
C27C7.5
Official Full Name
Galectin
Primary source
WormBase:WBGene00007768
Locus tag
CELE_C27C7.5
See related
AllianceGenome:WB:WBGene00007768
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable carbohydrate binding activity and galactoside binding activity. Orthologous to several human genes including CLC (Charcot-Leyden crystal galectin); LGALS12 (galectin 12); and LGALS13 (galectin 13). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See C27C7.5 in Genome Data Viewer
Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003279.8 (11423993..11426054, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene protein of unknown function WSN domain-containing protein Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nuclear receptor domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables galactoside binding IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Galectin
NP_001263496.1
  • Partially confirmed by transcript evidence
NP_492918.2
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    11423993..11426054 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001276567.2 → NP_001263496.1  Galectin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001263496.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    K8ERT0
    Conserved Domains (2) summary
    smart00605
    Location:17 → 109
    CW; CW domain
    pfam00337
    Location:149 → 271
    Gal-bind_lectin; Galactoside-binding lectin

  2. NM_060517.6 → NP_492918.2  Galectin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492918.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XVD0
    Conserved Domains (2) summary
    smart00605
    Location:1 → 91
    CW; CW domain
    cd00070
    Location:131 → 258
    GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...
Nucleotide Protein
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Gene LinkOut

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