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trhr-1 Thyrotropin-releasing hormone receptor [ Caenorhabditis elegans ]

Gene ID: 183056, updated on 9-Dec-2024

Summary

Official Symbol
trhr-1
Official Full Name
Thyrotropin-releasing hormone receptor
Primary source
WormBase:WBGene00016265
Locus tag
CELE_C30F12.6
See related
AllianceGenome:WB:WBGene00016265
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable thyrotropin-releasing hormone receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Is expressed in intestine and pharynx. Human ortholog(s) of this gene implicated in congenital nongoitrous hypothyroidism 7 and hypertension. Orthologous to human TRHR (thyrotropin releasing hormone receptor). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See trhr-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (6989067..6992108)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Isocitrate dehydrogenase [NAD] subunit, mitochondrial Neighboring gene ncRNA Neighboring gene AbLIM_anchor domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables thyrotropin-releasing hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Thyrotropin-releasing hormone receptor
NP_491990.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6989067..6992108
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059589.8NP_491990.1  Thyrotropin-releasing hormone receptor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491990.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q95YD7
    Conserved Domains (1) summary
    cd14995
    Location:33349
    7tmA_TRH-R; thyrotropin-releasing hormone receptor, member of the class A family of seven-transmembrane G protein-coupled receptors