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cyp-25A1 Cytochrome P450 [ Caenorhabditis elegans ]

Gene ID: 183247, updated on 2-Nov-2024

Summary

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Official Symbol
cyp-25A1
Official Full Name
Cytochrome P450
Primary source
WormBase:WBGene00007963
Locus tag
CELE_C36A4.1
See related
AllianceGenome:WB:WBGene00007963
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cyp-25A1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
8
Sequence:
Chromosome: III; NC_003281.10 (3832591..3834586)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Lysine-specific histone demethylase 1B homolog Neighboring gene Metal transporter cnnm-5 Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene Cytochrome P450 Neighboring gene Cytochrome P450

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans. Ladage ML, et al. G3 (Bethesda), 2016 Oct 13. PMID 27507791, Free PMC Article
  2. A systems biology analysis of reproductive toxicity effects induced by multigenerational exposure to ionizing radiation in C. elegans. Guédon R, et al. Ecotoxicol Environ Saf, 2021 Dec 1. PMID 34544019
  3. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
  4. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cytochrome P450
NP_497775.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    3832591..3834586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065374.5 → NP_497775.3  Cytochrome P450 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497775.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q27477
    Conserved Domains (1) summary
    cd11055
    Location:73 → 495
    CYP3A-like; cytochrome P450 family 3, subfamily A and similar cytochrome P450s
Nucleotide Protein
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