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ppm-1.H PPM-type phosphatase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 183398, updated on 4-Jan-2025

Summary

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Official Symbol
ppm-1.H
Official Full Name
PPM-type phosphatase domain-containing protein
Primary source
WormBase:WBGene00016580
Locus tag
CELE_C42C1.2
See related
AllianceGenome:WB:WBGene00016580
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity. Predicted to be involved in signal transduction. Predicted to be active in mitochondrion. Orthologous to several human genes including PPM1J (protein phosphatase, Mg2+/Mn2+ dependent 1J). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ppm-1.H in Genome Data Viewer
Location:
chromosome: IV
Exon count:
8
Sequence:
Chromosome: IV; NC_003282.8 (12264659..12268322, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class E (Epsilon) Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein eL34

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
PPM-type phosphatase domain-containing protein
NP_502329.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    12264659..12268322 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069928.6 → NP_502329.3  PPM-type phosphatase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_502329.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    A3QMB1
    Conserved Domains (1) summary
    cd00143
    Location:171 → 518
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...
Nucleotide Protein
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