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gasr-8 uncharacterized protein [ Caenorhabditis elegans ]

Gene ID: 183553, updated on 9-Dec-2024

Summary

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Official Symbol
gasr-8
Official Full Name
uncharacterized protein
Primary source
WormBase:WBGene00008144
Locus tag
CELE_C47E8.6
See related
AllianceGenome:WB:WBGene00008144
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable microtubule binding activity and small GTPase binding activity. Predicted to be involved in cell motility. Located in ciliary basal body. Is expressed in ciliated neurons; head neurons; sensory neurons; and tail neurons. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 33. Orthologous to human GAS8 (growth arrest specific 8). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See gasr-8 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (14689110..14691976)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Heat shock protein 90 Neighboring gene Secreted protein Neighboring gene tRNA-Tyr Neighboring gene ncRNA Neighboring gene Protein unc-112 Neighboring gene SET domain-containing protein;SPK domain-containing protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis. Nechipurenko IV, et al. Dev Cell, 2016 Sep 12. PMID 27623382, Free PMC Article
  2. Functional genomics of the cilium, a sensory organelle. Blacque OE, et al. Curr Biol, 2005 May 24. PMID 15916950
  3. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell motility IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_506627.3
  • Product from WormBase gene class gasr;
    Confirmed by transcript evidence; GAS (human Growth Arrest-Specific) Related

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14689110..14691976
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074226.5 → NP_506627.3  uncharacterized protein CELE_C47E8.6 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506627.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18689
    Conserved Domains (1) summary
    COG1196
    Location:64 → 409
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein
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