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C53A5.11 Kelch-like protein 10 [ Caenorhabditis elegans ]

Gene ID: 183741, updated on 9-Dec-2024

Summary

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Official Symbol
C53A5.11
Official Full Name
Kelch-like protein 10
Primary source
WormBase:WBGene00008269
Locus tag
CELE_C53A5.11
See related
AllianceGenome:WB:WBGene00008269
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See C53A5.11 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (14562889..14564639)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Kelch repeat protein Neighboring gene Serpentine Receptor, class T Neighboring gene Muscarinic acetylcholine receptor gar-3 Neighboring gene ncRNA Neighboring gene Serine/threonine specific protein phosphatases domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ubiquitin-like ligase-substrate adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of Cul3-RING ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Kelch-like protein 10
NP_506607.2
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    14562889..14564639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_074206.2 → NP_506607.2  Kelch-like protein 10 [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17702
    Conserved Domains (2) summary
    sd00038
    Location:200 → 243
    Kelch; KELCH repeat [structural motif]
    cl28614
    Location:165 → 379
    BTB; Broad-Complex, Tramtrack and Bric a brac
Nucleotide Protein
Heading Accession and Version

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