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maco-1 Macoilin [ Caenorhabditis elegans ]

Gene ID: 183963, updated on 9-Dec-2024

Summary

Official Symbol
maco-1
Official Full Name
Macoilin
Primary source
WormBase:WBGene00017066
Locus tag
CELE_D2092.5
See related
AllianceGenome:WB:WBGene00017066
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable microtubule binding activity. Involved in chemotaxis; neuronal signal transduction; and thermotaxis. Located in neuronal cell body; nuclear envelope; and rough endoplasmic reticulum. Is expressed in epithelial cell; muscle cell; and nervous system. Orthologous to human MACO1 (macoilin 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See maco-1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
13
Sequence:
Chromosome: I; NC_003279.8 (6598982..6607520, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene SH2 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Thioredoxin domain-containing protein Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in chemotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in locomotion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neuronal signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neuronal signal transduction IEA
Inferred from Electronic Annotation
more info
 
involved_in neuronal signal transduction IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in thermotaxis IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nuclear membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in rough endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in rough endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in rough endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Macoilin
NP_491902.4
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    6598982..6607520 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059501.7NP_491902.4  Macoilin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491902.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P91193
    Conserved Domains (1) summary
    pfam09726
    Location:38707
    Macoilin; Transmembrane protein