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srh-234 Serpentine Receptor, class H [ Caenorhabditis elegans ]

Gene ID: 184136, updated on 4-Jan-2025

Summary

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Official Symbol
srh-234
Official Full Name
Serpentine Receptor, class H
Primary source
WormBase:WBGene00005441
Locus tag
CELE_F07C4.14
See related
AllianceGenome:WB:WBGene00005441
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in cilium. Is expressed in ADLL and ADLR. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See srh-234 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (7650242..7651857, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Seven TM Receptor Neighboring gene pseudo Neighboring gene Serpentine Receptor, class H Neighboring gene Protein sleepless

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dietary vitamin B12 regulates chemosensory receptor gene expression via the MEF2 transcription factor in Caenorhabditis elegans. McDonagh A, et al. G3 (Bethesda), 2022 May 30. PMID 35512190, Free PMC Article
  2. Plasticity of chemoreceptor gene expression: Sensory and circuit inputs modulate state-dependent chemoreceptors. Gruner M, et al. Worm, 2015 Apr-Jun. PMID 26430563, Free PMC Article
  3. Feeding state, insulin and NPR-1 modulate chemoreceptor gene expression via integration of sensory and circuit inputs. Gruner M, et al. PLoS Genet, 2014 Oct. PMID 25357003, Free PMC Article
  4. Cell-Autonomous and Non-Cell-Autonomous Regulation of a Feeding State-Dependent Chemoreceptor Gene via MEF-2 and bHLH Transcription Factors. Gruner M, et al. PLoS Genet, 2016 Aug. PMID 27487365, Free PMC Article
  5. KIN-29 SIK regulates chemoreceptor gene expression via an MEF2 transcription factor and a class II HDAC. van der Linden AM, et al. EMBO J, 2007 Jan 24. PMID 17170704, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables G protein-coupled receptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cilium IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
Serpentine Receptor, class H
NP_504982.1
  • Predicted

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    7650242..7651857 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072581.1 → NP_504982.1  Serpentine Receptor, class H [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504982.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9GS03
    Conserved Domains (1) summary
    pfam10318
    Location:11 → 305
    7TM_GPCR_Srh; Serpentine type 7TM GPCR chemoreceptor Srh
Nucleotide Protein
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