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tag-138 ENTH domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 184169, updated on 4-Jan-2025

Summary

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Official Symbol
tag-138
Official Full Name
ENTH domain-containing protein
Primary source
WormBase:WBGene00006484
Locus tag
CELE_F08A8.6
See related
AllianceGenome:WB:WBGene00006484
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable several functions, including anion binding activity; clathrin adaptor activity; and clathrin light chain binding activity. Predicted to be involved in actin filament organization; clathrin coat assembly; and endocytosis. Predicted to be active in clathrin-coated vesicle and cortical actin cytoskeleton. Orthologous to human HIP1R (huntingtin interacting protein 1 related). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See tag-138 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (12934764..12937362)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene CP2 domain-containing protein Neighboring gene pseudo Neighboring gene Acyl-coenzyme A oxidase acox-1.1 Neighboring gene Acyl-coenzyme A oxidase acox-1.2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables clathrin adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables clathrin binding IEA
Inferred from Electronic Annotation
more info
  
enables clathrin light chain binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-3,4-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-3,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in clathrin coat assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in clathrin-coated vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cortical actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ENTH domain-containing protein
NP_493260.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    12934764..12937362
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_060859.2 → NP_493260.1  ENTH domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_493260.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62142
    Conserved Domains (2) summary
    pfam07651
    Location:13 → 276
    ANTH; ANTH domain
    cl03075
    Location:295 → 333
    GrpE; nucleotide exchange factor GrpE
Nucleotide Protein
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