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clec-7 C-type LECtin [ Caenorhabditis elegans ]

Gene ID: 184314, updated on 9-Dec-2024

Summary

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Official Symbol
clec-7
Official Full Name
C-type LECtin
Primary source
WormBase:WBGene00017364
Locus tag
CELE_F10G2.3
See related
AllianceGenome:WB:WBGene00017364
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in defense response to Gram-positive bacterium. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See clec-7 in Genome Data Viewer
Location:
chromosome: V
Exon count:
4
Sequence:
Chromosome: V; NC_003283.11 (7328392..7330002)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein;G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene DUF19 domain-containing protein Neighboring gene UPF0376 protein F10G2.1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Per- and polyfluoroalkyl substances enhance Staphylococcus aureus pathogenicity and impair host immune response. Mangu JCK, et al. Environ Pollut, 2022 Dec 1. PMID 36181932
  2. Defective apoptotic cell clearance activates innate immune response to protect Caenorhabditis elegans against pathogenic bacteria. Wan J, et al. Virulence, 2021 Dec. PMID 33372828, Free PMC Article
  3. Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes. Visvikis O, et al. Immunity, 2014 Jun 19. PMID 24882217, Free PMC Article
  4. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
  5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in defense response to Gram-positive bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
C-type LECtin
NP_504865.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    7328392..7330002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072464.5 → NP_504865.1  C-type LECtin [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504865.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22955
    Conserved Domains (2) summary
    smart00034
    Location:25 → 152
    CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    cd00041
    Location:308 → 412
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
Nucleotide Protein
Heading Accession and Version

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