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cdc-50.B Cell cycle control protein 50A [ Caenorhabditis elegans ]

Gene ID: 184717, updated on 9-Dec-2024

Summary

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Official Symbol
cdc-50.B
Official Full Name
Cell cycle control protein 50A
Primary source
WormBase:WBGene00008969
Locus tag
CELE_F20C5.4
See related
AllianceGenome:WB:WBGene00008969
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in innate immune response. Predicted to be located in membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Orthologous to human TMEM30B (transmembrane protein 30B). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See cdc-50.B in Genome Data Viewer
Location:
chromosome: IV
Exon count:
7
Sequence:
Chromosome: IV; NC_003282.8 (8764867..8767447)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Enlarged germline granules protein 1 Neighboring gene Uncharacterized protein Neighboring gene Kinesin-like protein Neighboring gene ncRNA Neighboring gene PACT_coil_coil domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Extracellular vesicle budding is inhibited by redundant regulators of TAT-5 flippase localization and phospholipid asymmetry. Beer KB, et al. Proc Natl Acad Sci U S A, 2018 Feb 6. PMID 29367422, Free PMC Article
  2. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in innate immune response HEP PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Cell cycle control protein 50A
NP_501511.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    8764867..8767447
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_069110.5 → NP_501511.1  Cell cycle control protein 50A [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_501511.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q19635
    Conserved Domains (1) summary
    pfam03381
    Location:67 → 353
    CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family
Nucleotide Protein
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