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amx-3 Amine oxidase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 184919, updated on 9-Dec-2024

Summary

Official Symbol
amx-3
Official Full Name
Amine oxidase domain-containing protein
Primary source
WormBase:WBGene00000139
Locus tag
CELE_F25C8.2
See related
AllianceGenome:WB:WBGene00000139
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable polyamine oxidase activity. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human PAOX (polyamine oxidase) and SMOX (spermine oxidase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See amx-3 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (20898840..20903714, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein unc-80 Neighboring gene ncRNA Neighboring gene 4-coumarate--CoA ligase 1-like Neighboring gene pseudo

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables polyamine oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Amine oxidase domain-containing protein
NP_001256964.1
  • Confirmed by transcript evidence
NP_001355373.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    20898840..20903714 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001368491.3NP_001355373.1  Amine oxidase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    E0AHD3
    Conserved Domains (1) summary
    pfam01593
    Location:11443
    Amino_oxidase; Flavin containing amine oxidoreductase
  2. NM_001270035.3NP_001256964.1  Amine oxidase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001256964.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E0AHD4
    Conserved Domains (1) summary
    pfam01593
    Location:3358
    Amino_oxidase; Flavin containing amine oxidoreductase