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twk-47 Potassium channel domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 185227, updated on 4-Jan-2025

Summary

Official Symbol
twk-47
Official Full Name
Potassium channel domain-containing protein
Primary source
WormBase:WBGene00018002
Locus tag
CELE_F33D11.5
See related
AllianceGenome:WB:WBGene00018002
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human KCNK17 (potassium two pore domain channel subfamily K member 17) and KCNK5 (potassium two pore domain channel subfamily K member 5). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See twk-47 in Genome Data Viewer
Location:
chromosome: I
Exon count:
8
Sequence:
Chromosome: I; NC_003279.8 (5834597..5837392, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Nuclear hormone receptor family member nhr-2 Neighboring gene alanine transaminase Neighboring gene ncRNA Neighboring gene Oxysterol-binding protein Neighboring gene Uncharacterized protein Neighboring gene Homeobox domain-containing protein;Homeobox protein ceh-12

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables outward rectifier potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
 
enables potassium ion leak channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Potassium channel domain-containing protein
NP_001309491.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    5834597..5837392 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001322673.2NP_001309491.1  Potassium channel domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44773
    Conserved Domains (1) summary
    pfam07885
    Location:124180
    Ion_trans_2; Ion channel