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ztf-28 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 185364, updated on 4-Jan-2025

Summary

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Official Symbol
ztf-28
Official Full Name
C2H2-type domain-containing protein
Primary source
WormBase:WBGene00018099
Locus tag
CELE_F36F12.8
See related
AllianceGenome:WB:WBGene00018099
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in intestine. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ztf-28 in Genome Data Viewer
Location:
chromosome: V
Exon count:
3
Sequence:
Chromosome: V; NC_003283.11 (2090669..2091740)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Lipase_GDSL domain-containing protein;Phospholipase B1, membrane-associated Neighboring gene Cytosolic fatty-acid binding proteins domain-containing protein;Fatty acid-binding protein homolog 9 Neighboring gene Glycosyltransferase family 92 protein Neighboring gene Glycosyltransferase family 92 protein Neighboring gene C-type lectin domain-containing protein Neighboring gene C-type lectin domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A left/right asymmetric neuronal differentiation program is controlled by the Caenorhabditis elegans lsy-27 zinc-finger transcription factor. Zhang F, et al. Genetics, 2011 Jul. PMID 21555395, Free PMC Article
  2. Individual cell types in C. elegans age differently and activate distinct cell-protective responses. Roux AE, et al. Cell Rep, 2023 Aug 29. PMID 37531250
  3. Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Styer KL, et al. Science, 2008 Oct 17. PMID 18801967, Free PMC Article
  4. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
  5. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
C2H2-type domain-containing protein
NP_503566.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    2090669..2091740
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071165.4 → NP_503566.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503566.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O76398
    Conserved Domains (2) summary
    COG5236
    Location:14 → 114
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    sd00017
    Location:42 → 63
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein
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