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gst-18 Glutathione S-transferase [ Caenorhabditis elegans ]

Gene ID: 185412, updated on 9-Dec-2024

Summary

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Official Symbol
gst-18
Official Full Name
Glutathione S-transferase
Primary source
WormBase:WBGene00001766
Locus tag
CELE_F37B1.7
See related
AllianceGenome:WB:WBGene00001766
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable glutathione transferase activity. Predicted to be involved in glutathione metabolic process. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See gst-18 in Genome Data Viewer
Location:
chromosome: II
Exon count:
2
Sequence:
Chromosome: II; NC_003280.10 (13629799..13630887, complement)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Glutathione S-Transferase Neighboring gene Glutathione S-Transferase Neighboring gene GST C-terminal domain-containing protein Neighboring gene DPPIV_N domain-containing protein;Protein TolB;Translocation protein TolB Neighboring gene D-3-phosphoglycerate dehydrogenase Neighboring gene F-box domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Life span and stress resistance of Caenorhabditis elegans are differentially affected by glutathione transferases metabolizing 4-hydroxynon-2-enal. Ayyadevara S, et al. Mech Ageing Dev, 2007 Feb. PMID 17157356, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables glutathione transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutathione transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Glutathione S-transferase
NP_496866.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13629799..13630887 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064465.1 → NP_496866.1  Glutathione S-transferase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496866.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q93700
    Conserved Domains (3) summary
    PTZ00057
    Location:6 → 192
    PTZ00057; glutathione s-transferase; Provisional
    cd03192
    Location:73 → 179
    GST_C_Sigma_like; C-terminal, alpha helical domain of Class Sigma-like Glutathione S-transferases
    cd03039
    Location:4 → 63
    GST_N_Sigma_like; GST_N family, Class Sigma_like; composed of GSTs belonging to class Sigma and similar proteins, including GSTs from class Mu, Pi and Alpha. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of ...
Nucleotide Protein
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