U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cysl-4 Cysteine synthase [ Caenorhabditis elegans ]

Gene ID: 186587, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
cysl-4
Official Full Name
Cysteine synthase
Primary source
WormBase:WBGene00019096
Locus tag
CELE_F59A7.9
See related
AllianceGenome:WB:WBGene00019096
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cysteine synthase activity. Predicted to be involved in cysteine biosynthetic process from serine. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cysl-4 in Genome Data Viewer
Location:
chromosome: V
Exon count:
6
Sequence:
Chromosome: V; NC_003283.11 (2004959..2006805)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Aldehyde dehydrogenase Neighboring gene C-type lectin domain-containing protein Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Biochemical properties of nematode O-acetylserine(thiol)lyase paralogs imply their distinct roles in hydrogen sulfide homeostasis. Vozdek R, et al. Biochim Biophys Acta, 2013 Dec. PMID 24100226
  2. The response of Caenorhabditis elegans to hydrogen sulfide and hydrogen cyanide. Budde MW, et al. Genetics, 2011 Oct. PMID 21840852, Free PMC Article
  3. Sulfurous gases as biological messengers and toxins: comparative genetics of their metabolism in model organisms. Mathew ND, et al. J Toxicol, 2011. PMID 22131987, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cysteine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cysteine synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cysteine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in cysteine biosynthetic process from serine IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cysteine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Cysteine synthase
NP_503547.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    2004959..2006805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_071146.2 → NP_503547.1  Cysteine synthase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_503547.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O16284
    Conserved Domains (2) summary
    cd01561
    Location:15 → 305
    CBS_like; CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. ...
    PLN02565
    Location:9 → 319
    PLN02565; cysteine synthase
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools