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K05B2.4 Acyl-coenzyme A thioesterase 1-like [ Caenorhabditis elegans ]

Gene ID: 187017, updated on 2-Nov-2024

Summary

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Official Symbol
K05B2.4
Official Full Name
Acyl-coenzyme A thioesterase 1-like
Primary source
WormBase:WBGene00019404
Locus tag
CELE_K05B2.4
See related
AllianceGenome:WB:WBGene00019404
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Human ortholog(s) of this gene implicated in disease of metabolism. Orthologous to several human genes including ACOT1 (acyl-CoA thioesterase 1); ACOT2 (acyl-CoA thioesterase 2); and ACOT4 (acyl-CoA thioesterase 4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See K05B2.4 in Genome Data Viewer
Location:
chromosome: X
Exon count:
9
Sequence:
Chromosome: X; NC_003284.9 (4918988..4920992, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene RAB6-interacting golgin;Ras-associating domain-containing protein Neighboring gene Intermediate filament protein ifa-4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
  2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables fatty acyl-CoA hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables thiolester hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in acyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Acyl-coenzyme A thioesterase 1-like
NP_508837.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    4918988..4920992 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_076436.5 → NP_508837.3  Acyl-coenzyme A thioesterase 1-like [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_508837.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9GYN3
    Conserved Domains (2) summary
    pfam04775
    Location:16 → 133
    Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
    pfam08840
    Location:208 → 417
    BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal
Nucleotide Protein
Heading Accession and Version

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