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M05B5.1 Tyrosine-protein phosphatase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 187450, updated on 9-Dec-2024

Summary

Official Symbol
M05B5.1
Official Full Name
Tyrosine-protein phosphatase domain-containing protein
Primary source
WormBase:WBGene00010869
Locus tag
CELE_M05B5.1
See related
AllianceGenome:WB:WBGene00010869
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See M05B5.1 in Genome Data Viewer
Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003279.8 (7177904..7179430, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ion_trans domain-containing protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Tyrosine-protein phosphatase domain-containing protein
NP_492030.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7177904..7179430 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059629.2NP_492030.1  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492030.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q21514
    Conserved Domains (3) summary
    smart00194
    Location:91409
    PTPc; Protein tyrosine phosphatase, catalytic domain
    pfam06459
    Location:978
    RR_TM4-6; Ryanodine Receptor TM 4-6
    cl21483
    Location:118392
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...