npr-20 G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Official Symbol: npr-20
Official Full Name: G-protein coupled receptors family 1 profile domain-containing protein
Primary source: WormBase:WBGene00011578
Locus tag: CELE_T07D4.1
See related: AllianceGenome:WB:WBGene00011578
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); hematologic cancer (multiple); and pyelonephritis (multiple). Orthologous to several human genes including CCR1 (C-C motif chemokine receptor 1); CCR10 (C-C motif chemokine receptor 10); and CCR2 (C-C motif chemokine receptor 2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

Preferred Names: G-protein coupled receptors family 1 profile domain-containing protein

NP_495888.3

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The following sections contain reference sequences that belong to a specific genome build. Explain