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sld-2 Ribosome biogenesis protein NOP53 [ Caenorhabditis elegans ]

Gene ID: 188455, updated on 4-Jan-2025

Summary

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Official Symbol
sld-2
Official Full Name
Ribosome biogenesis protein NOP53
Primary source
WormBase:WBGene00020466
Locus tag
CELE_T12F5.1
See related
AllianceGenome:WB:WBGene00020466
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Is expressed in several structures, including AB; EMS; Psub1; Psub2; and germ line. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See sld-2 in Genome Data Viewer
Location:
chromosome: I
Exon count:
6
Sequence:
Chromosome: I; NC_003279.8 (3741451..3742647)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ATP-dependent RNA helicase glh-4 Neighboring gene RING-type domain-containing protein Neighboring gene HTH La-type RNA-binding domain-containing protein Neighboring gene ncRNA Neighboring gene MATH (meprin-associated Traf homology) domain containing Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans. Gaggioli V, et al. PLoS Genet, 2020 Dec. PMID 33320862, Free PMC Article
  2. CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans. Gaggioli V, et al. J Cell Biol, 2014 Feb 17. PMID 24535824, Free PMC Article
  3. DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans. Xia Y, et al. Science, 2023 Sep 22. PMID 37590372, Free PMC Article
  4. Domain selection combined with improved cloning strategy for high throughput expression of higher eukaryotic proteins. Chen Y, et al. BMC Biotechnol, 2007 Jul 30. PMID 17663785, Free PMC Article
  5. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans.
    Title: Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

General protein information

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Preferred Names
Ribosome biogenesis protein NOP53
NP_491210.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    3741451..3742647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058809.6 → NP_491210.1  Ribosome biogenesis protein NOP53 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_491210.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O44761
Nucleotide Protein
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