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lgc-54 Ligand-Gated ion Channel [ Caenorhabditis elegans ]

Gene ID: 188525, updated on 14-Nov-2024

Summary

Official Symbol
lgc-54
Official Full Name
Ligand-Gated ion Channel
Primary source
WormBase:WBGene00020528
Locus tag
CELE_T15B7.16
See related
AllianceGenome:WB:WBGene00020528
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and neurotransmitter receptor activity. Predicted to contribute to chloride channel activity. Predicted to be involved in chemical synaptic transmission; chloride transmembrane transport; and regulation of membrane potential. Predicted to be located in membrane and postsynapse. Predicted to be part of transmembrane transporter complex. Predicted to be active in neuron projection; plasma membrane; and synapse. Is expressed in AVEL; AVER; RMHL; and RMHR. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See lgc-54 in Genome Data Viewer
Location:
chromosome: V
Exon count:
10
Sequence:
Chromosome: V; NC_003283.11 (6840217..6846607, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene Chloride channel CLIC-like protein 1 Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene GRIP domain-containing protein Neighboring gene Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase hpo-8 Neighboring gene Fibrinogen C-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
contributes_to chloride channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables excitatory extracellular ligand-gated monoatomic ion channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables extracellular ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
 
enables monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chloride transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in excitatory postsynaptic potential IEA
Inferred from Electronic Annotation
more info
 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Ligand-Gated ion Channel
NP_001343648.1
  • Product from WormBase gene class lgc;
    Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6840217..6846607 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356670.2NP_001343648.1  Ligand-Gated ion Channel [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    O17041
    Conserved Domains (1) summary
    cl27321
    Location:55474
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain