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tsct-1 Protein tsct-1 [ Caenorhabditis elegans ]

Gene ID: 188577, updated on 9-Dec-2024

Summary

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Official Symbol
tsct-1
Official Full Name
Protein tsct-1
Primary source
WormBase:WBGene00011824
Locus tag
CELE_T18D3.7
See related
AllianceGenome:WB:WBGene00011824
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in anal region; body wall musculature; head; neurons; and pharynx. Orthologous to several human genes including TSC22D3 (TSC22 domain family member 3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See tsct-1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
7
Sequence:
Chromosome: X; NC_003284.9 (12434097..12443915)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Ovule protein Neighboring gene GATA-type domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Mitochondrial inner membrane protein Mpv17 Neighboring gene WD repeat-containing protein 89

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Investigating the role of RIO protein kinases in Caenorhabditis elegans. Mendes TK, et al. PLoS One, 2015. PMID 25688864, Free PMC Article
  2. Prefoldin 6 mediates longevity response from heat shock factor 1 to FOXO in C. elegans. Son HG, et al. Genes Dev, 2018 Dec 1. PMID 30478249, Free PMC Article
  3. A 4D single-cell protein atlas of transcription factors delineates spatiotemporal patterning during embryogenesis. Ma X, et al. Nat Methods, 2021 Aug. PMID 34312566
  4. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
  5. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
Protein tsct-1
NP_001257192.1
  • Confirmed by transcript evidence
NP_001366745.1
  • Confirmed by transcript evidence
NP_001368132.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    12434097..12443915
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001270263.3 → NP_001257192.1  Protein tsct-1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001257192.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    I2HAB1, I2HAB2, Q22544
    Conserved Domains (1) summary
    pfam01166
    Location:210 → 266
    TSC22; TSC-22/dip/bun family

  2. NM_001381118.1 → NP_001368132.1  Protein tsct-1 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    pfam01166
    Location:196 → 252
    TSC22; TSC-22/dip/bun family

  3. NM_001381119.1 → NP_001366745.1  Protein tsct-1 [Caenorhabditis elegans]

    Status: REVIEWED

    Conserved Domains (1) summary
    pfam01166
    Location:72 → 128
    TSC22; TSC-22/dip/bun family
Nucleotide Protein
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