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pho-7 Lysosomal acid phosphatase [ Caenorhabditis elegans ]

Gene ID: 188683, updated on 4-Jan-2025

Summary

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Official Symbol
pho-7
Official Full Name
Lysosomal acid phosphatase
Primary source
WormBase:WBGene00011879
Locus tag
CELE_T21B6.2
See related
AllianceGenome:WB:WBGene00011879
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable phosphatase activity. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J. Orthologous to human ACP2 (acid phosphatase 2, lysosomal) and ACP4 (acid phosphatase 4). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See pho-7 in Genome Data Viewer
Location:
chromosome: X
Exon count:
10
Sequence:
Chromosome: X; NC_003284.9 (10938194..10941355, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Apple domain-containing protein Neighboring gene ncRNA Neighboring gene Secreted protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Lysosomal acid phosphatase
NP_509828.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    10938194..10941355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077427.8 → NP_509828.2  Lysosomal acid phosphatase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_509828.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22630
    Conserved Domains (1) summary
    cd07061
    Location:18 → 313
    HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction
Nucleotide Protein
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