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ilc-17.1 Interleukin cytokine-related protein 17.1 [ Caenorhabditis elegans ]

Gene ID: 188767, updated on 9-Dec-2024

Summary

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Official Symbol
ilc-17.1
Official Full Name
Interleukin cytokine-related protein 17.1
Primary source
WormBase:WBGene00011937
Locus tag
CELE_T22H6.1
See related
AllianceGenome:WB:WBGene00011937
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable cytokine activity. Involved in positive regulation of locomotion and response to oxygen levels. Located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ilc-17.1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
6
Sequence:
Chromosome: X; NC_003284.9 (12766818..12769797, complement)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Nuclear hormone receptor family member nhr-27 Neighboring gene ncRNA Neighboring gene Choline/ethanolaminephosphotransferase 1-like Neighboring gene Glutamate 5-kinase Neighboring gene Seven TM Receptor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53. Godthi A, et al. Proc Natl Acad Sci U S A, 2024 Mar 19. PMID 38483995, Free PMC Article
  2. IL-17: good fear no tears. Rua R, et al. Nat Immunol, 2020 Nov. PMID 32958929
  3. IL-17 is a neuromodulator of Caenorhabditis elegans sensory responses. Chen C, et al. Nature, 2017 Feb 2. PMID 28099418, Free PMC Article
  4. MALT-1 mediates IL-17 neural signaling to regulate C. elegans behavior, immunity and longevity. Flynn SM, et al. Nat Commun, 2020 Apr 29. PMID 32350248, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of locomotion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to oxygen levels IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Interleukin cytokine-related protein 17.1
NP_510131.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    12766818..12769797 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077730.4 → NP_510131.2  Interleukin cytokine-related protein 17.1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510131.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q22687
    Conserved Domains (1) summary
    pfam06083
    Location:123 → 198
    IL17; Interleukin-17
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q22687.2

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