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T27A8.3 Putative uncharacterized protein T27A8.3 [ Caenorhabditis elegans ]

Gene ID: 188968, updated on 4-Jan-2025

Summary

Official Symbol
T27A8.3
Official Full Name
Putative uncharacterized protein T27A8.3
Primary source
WormBase:WBGene00012075
Locus tag
CELE_T27A8.3
See related
AllianceGenome:WB:WBGene00012075
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable aminopeptidase activity and metalloexopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. Orthologous to human METAP2 (methionyl aminopeptidase 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See T27A8.3 in Genome Data Viewer
Location:
chromosome: X
Exon count:
2
Sequence:
Chromosome: X; NC_003284.9 (16062685..16063290)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Fork-head domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene Col_cuticle_N domain-containing protein Neighboring gene Neuropeptide-Like Protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables aminopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables aminopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
enables metalloexopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Putative uncharacterized protein T27A8.3
NP_510627.1
  • Predicted

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    16062685..16063290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078226.1NP_510627.1  Putative uncharacterized protein T27A8.3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510627.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P50581
    Conserved Domains (1) summary
    cl00279
    Location:37151
    APP_MetAP; A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity ...