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T28F4.3 Protein-tyrosine phosphatase [ Caenorhabditis elegans ]

Gene ID: 189059, updated on 2-Nov-2024

Summary

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Official Symbol
T28F4.3
Official Full Name
Protein-tyrosine phosphatase
Primary source
WormBase:WBGene00012138
Locus tag
CELE_T28F4.3
See related
AllianceGenome:WB:WBGene00012138
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance and signal transduction. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See T28F4.3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
7
Sequence:
Chromosome: I; NC_003279.8 (7484062..7486293, complement)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Degenerin-like protein asic-2 Neighboring gene Inverted formin-2;PUM-HD domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in motor neuron axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Protein-tyrosine phosphatase
NP_492100.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    7484062..7486293 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_059699.3 → NP_492100.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_492100.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22852
    Conserved Domains (2) summary
    smart00194
    Location:58 → 312
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:86 → 312
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
Nucleotide Protein
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Gene LinkOut

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