apt-9 ADP-ribosylation factor-binding protein GGA1 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: apt-9
Official Full Name: ADP-ribosylation factor-binding protein GGA1
Primary source: WormBase:WBGene00000166
Locus tag: CELE_W04G3.4
See related: AllianceGenome:WB:WBGene00000166
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable small GTPase binding activity. Involved in protein secretion. Predicted to be located in Golgi apparatus and early endosome membrane. Predicted to be active in trans-Golgi network. Orthologous to several human genes including GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See apt-9 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 13

Sequence:: Chromosome: X; NC_003284.9 (11068527..11072047)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

W04G3.4 (e-PCR)
- UniSTS:311134

STS6-179 (e-PCR)
- UniSTS:242561

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables phosphatidylinositol binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables small GTPase binding	IBA Inferred from Biological aspect of Ancestor more info
enables small GTPase binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in Golgi to plasma membrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in protein localization to cell surface	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein secretion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in early endosome membrane	IEA Inferred from Electronic Annotation more info
is_active_in trans-Golgi network	IBA Inferred from Biological aspect of Ancestor more info
located_in trans-Golgi network	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ADP-ribosylation factor-binding protein GGA1

NP_509853.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

11068527..11072047

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_077452.6 → NP_509853.2 ADP-ribosylation factor-binding protein GGA1 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_509853.2

Status: REVIEWED

UniProtKB/TrEMBL

Q23165

Conserved Domains (1) summary

cl02544
Location:8 → 147

VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...