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Y38F2AR.12 5-oxoprolinase;Hydantoinase B/oxoprolinase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 189679, updated on 9-Dec-2024

Summary

Official Symbol
Y38F2AR.12
Official Full Name
5-oxoprolinase;Hydantoinase B/oxoprolinase domain-containing protein
Primary source
WormBase:WBGene00021430
Locus tag
CELE_Y38F2AR.12
See related
AllianceGenome:WB:WBGene00021430
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable 5-oxoprolinase (ATP-hydrolyzing) activity. Predicted to be involved in glutathione metabolic process. Predicted to be active in cytosol. Orthologous to human OPLAH (5-oxoprolinase, ATP-hydrolysing). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See Y38F2AR.12 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
14
Sequence:
Chromosome: IV; NC_003282.8 (2399484..2412420, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein;Tudor domain-containing protein Neighboring gene ncRNA Neighboring gene Major sperm protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RING-type domain-containing protein Neighboring gene ncRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables 5-oxoprolinase (ATP-hydrolyzing) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
5-oxoprolinase;Hydantoinase B/oxoprolinase domain-containing protein
NP_001076725.2
  • Confirmed by transcript evidence
NP_001294530.1
  • Confirmed by transcript evidence
NP_001379804.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    2399484..2412420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001083256.4NP_001076725.2  5-oxoprolinase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001076725.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A9S2
    Conserved Domains (1) summary
    PLN02666
    Location:11255
    PLN02666; 5-oxoprolinase
  2. NM_001392265.1NP_001379804.1  Hydantoinase B/oxoprolinase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q86FM9
    Conserved Domains (1) summary
    PLN02666
    Location:23514
    PLN02666; 5-oxoprolinase
  3. NM_001307601.3NP_001294530.1  5-oxoprolinase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001294530.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    U4PMK1
    Conserved Domains (1) summary
    PLN02666
    Location:1941
    PLN02666; 5-oxoprolinase