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lact-9 Beta-lactamase-related domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 189927, updated on 4-Jan-2025

Summary

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Official Symbol
lact-9
Official Full Name
Beta-lactamase-related domain-containing protein
Primary source
WormBase:WBGene00012890
Locus tag
CELE_Y45F10D.11
See related
AllianceGenome:WB:WBGene00012890
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable peptidase activity. Predicted to be involved in proteolysis and regulation of lipid metabolic process. Predicted to be active in mitochondrion. Orthologous to human LACTB (lactamase beta). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See lact-9 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (13782383..13785645, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Transmembrane protein Neighboring gene Large ribosomal subunit protein eL18 Neighboring gene Putative polypeptide N-acetylgalactosaminyltransferase 10;Ricin B lectin domain-containing protein Neighboring gene NIF system FeS cluster assembly NifU N-terminal domain-containing protein Neighboring gene Integrin Cytoplasmic domain-Associated Protein homolog Neighboring gene Spindle assembly abnormal protein 6 Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene Abnormal cell migration protein 18-like fibronectin type I domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification, genomic organization, and mRNA expression of LACTB, encoding a serine beta-lactamase-like protein with an amino-terminal transmembrane domain. Smith TS, et al. Genomics, 2001 Nov. PMID 11707067
  2. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Beta-lactamase-related domain-containing protein
NP_001041033.1
  • Confirmed by transcript evidence
NP_001041034.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    13782383..13785645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001047568.4 → NP_001041033.1  Beta-lactamase-related domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041033.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    O62481
    Conserved Domains (1) summary
    pfam00144
    Location:44 → 406
    Beta-lactamase

  2. NM_001047569.3 → NP_001041034.1  Beta-lactamase-related domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001041034.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q2HQM1
    Conserved Domains (1) summary
    cl21491
    Location:1 → 166
    Transpeptidase; Penicillin binding protein transpeptidase domain
Nucleotide Protein
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