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mfsd-8.3 MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 190242, updated on 4-Jan-2025

Summary

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Official Symbol
mfsd-8.3
Official Full Name
MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein
Primary source
WormBase:WBGene00021814
Locus tag
CELE_Y53G8AR.7
See related
AllianceGenome:WB:WBGene00021814
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Predicted to be active in lysosomal membrane. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 7. Orthologous to human MFSD8 (major facilitator superfamily domain containing 8). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See mfsd-8.3 in Genome Data Viewer
Location:
chromosome: III
Exon count:
11
Sequence:
Chromosome: III; NC_003281.10 (3282308..3290205)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene RING-type domain-containing protein Neighboring gene HTH CENPB-type domain-containing protein Neighboring gene Mitochondrial ATP synthase regulatory component factor B Neighboring gene SAP domain-containing protein Neighboring gene RING-type domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein
NP_001022903.1
  • Confirmed by transcript evidence
NP_001380067.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    3282308..3290205
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001027732.5 → NP_001022903.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001022903.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N3G2
    Conserved Domains (1) summary
    cd17326
    Location:48 → 495
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

  2. NM_001393304.1 → NP_001380067.1  MFS domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YZM9
    Conserved Domains (1) summary
    cl28910
    Location:1 → 278
    MFS; Major Facilitator Superfamily
Nucleotide Protein
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