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Y69F12A.1 Protein kinase domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 190555, updated on 2-Nov-2024

Summary

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Official Symbol
Y69F12A.1
Official Full Name
Protein kinase domain-containing protein
Primary source
WormBase:WBGene00022102
Locus tag
CELE_Y69F12A.1
See related
AllianceGenome:WB:WBGene00022102
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Y69F12A.1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
6
Sequence:
Chromosome: III; NC_003281.10 (7456940..7458544)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Aldehyde dehydrogenase domain-containing protein Neighboring gene FIP (Fungus-Induced Protein) Related Neighboring gene FIP (Fungus-Induced Protein) Related

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Protein kinase domain-containing protein
NP_001367929.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7456940..7458544
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001379795.1 → NP_001367929.1  Protein kinase domain-containing protein [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9N4Q0
    Conserved Domains (1) summary
    cl21453
    Location:69 → 342
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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