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Y116A8C.27 ATP synthase mitochondrial F1 complex assembly factor 2;DUF3800 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 191004, updated on 4-Jan-2025

Summary

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Official Symbol
Y116A8C.27
Official Full Name
ATP synthase mitochondrial F1 complex assembly factor 2;DUF3800 domain-containing protein
Primary source
WormBase:WBGene00013804
Locus tag
CELE_Y116A8C.27
See related
AllianceGenome:WB:WBGene00013804
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in mitochondrial proton-transporting ATP synthase complex assembly. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 1. Orthologous to human ATPAF2 (ATP synthase mitochondrial F1 complex assembly factor 2). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See Y116A8C.27 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
6
Sequence:
Chromosome: IV; NC_003282.8 (17090640..17096268, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene PX domain-containing protein;PXA domain-containing protein;Sorting nexin-13 Neighboring gene Lipoprotein;Recep_L_domain domain-containing protein Neighboring gene Small nuclear ribonucleoprotein Sm D3 Neighboring gene ncRNA Neighboring gene Secreted protein Neighboring gene Carbonic anhydrase Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
  2. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
  3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in mitochondrial proton-transporting ATP synthase complex assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proton-transporting ATP synthase complex assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ATP synthase mitochondrial F1 complex assembly factor 2;DUF3800 domain-containing protein
NP_001255920.1
  • Confirmed by transcript evidence
NP_001255921.1
  • Partially confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    17090640..17096268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268991.5 → NP_001255920.1  ATP synthase mitochondrial F1 complex assembly factor 2 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255920.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9U2U3
    Conserved Domains (1) summary
    pfam07542
    Location:25 → 150
    ATP12; ATP12 chaperone protein

  2. NM_001268992.3 → NP_001255921.1  DUF3800 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255921.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D3NQA8
    Conserved Domains (1) summary
    cl02228
    Location:1 → 167
    ATP12; ATP12 chaperone protein
Nucleotide Protein
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