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dos-1 Delta and osm-11 homolog protein 1 [ Caenorhabditis elegans ]

Gene ID: 191338, updated on 2-Nov-2024

Summary

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Official Symbol
dos-1
Official Full Name
Delta and osm-11 homolog protein 1
Primary source
WormBase:WBGene00013980
Locus tag
CELE_ZK507.4
See related
AllianceGenome:WB:WBGene00013980
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable Notch binding activity. Predicted to be involved in positive regulation of Notch signaling pathway. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dos-1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (9103943..9106805)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene glp-1/Notch intracellular domain Neighboring gene Putative serine/threonine-protein kinase ZK507.1 Neighboring gene pseudo Neighboring gene tRNA-Asn Neighboring gene ncRNA Neighboring gene G2/mitotic-specific cyclin-A1 Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Ground-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development. Komatsu H, et al. PLoS Biol, 2008 Aug 12. PMID 18700817, Free PMC Article
  2. C. elegans Notch signaling regulates adult chemosensory response and larval molting quiescence. Singh K, et al. Curr Biol, 2011 May 24. PMID 21549604, Free PMC Article
  3. Notch signaling inhibits axon regeneration. El Bejjani R, et al. Neuron, 2012 Jan 26. PMID 22284182, Free PMC Article
  4. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables Notch binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in positive regulation of Notch signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Delta and osm-11 homolog protein 1
NP_499017.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    9103943..9106805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_066616.6 → NP_499017.2  Delta and osm-11 homolog protein 1 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_499017.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P34636
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34636.2

Gene LinkOut

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