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his-13 Histone H3 [ Caenorhabditis elegans ]

Gene ID: 191672, updated on 4-Jan-2025

Summary

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Official Symbol
his-13
Official Full Name
Histone H3
Primary source
WormBase:WBGene00001887
Locus tag
CELE_ZK131.7
See related
AllianceGenome:WB:WBGene00001887
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is expressed in nervous system. Orthologous to several human genes including H3C1 (H3 clustered histone 1); H3C10 (H3 clustered histone 10); and H3C11 (H3 clustered histone 11). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See his-13 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_003280.10 (13820210..13820620)

Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Histone H4 Neighboring gene Histone H2A Neighboring gene Histone H2B 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003280.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Histone gene expression and histone mRNA 3' end structure in Caenorhabditis elegans. Keall R, et al. BMC Mol Biol, 2007 Jun 14. PMID 17570845, Free PMC Article
  2. Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans. Nakano S, et al. Cell, 2011 Dec 23. PMID 22177093, Free PMC Article
  3. Nucleotide sequences of Caenorhabditis elegans core histone genes. Genes for different histone classes share common flanking sequence elements. Roberts SB, et al. J Mol Biol, 1989 Apr 20. PMID 2544730
  4. Evidence for dynamic alteration in histone gene clusters of Caenorhabditis elegans: a topoisomerase II connection? Holt SJ, et al. Genet Res, 2002 Feb. PMID 11974600
  5. The Caenorhabditis elegans histone hairpin-binding protein is required for core histone gene expression and is essential for embryonic and postembryonic cell division. Pettitt J, et al. J Cell Sci, 2002 Feb 15. PMID 11865041

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Histone H3
NP_496890.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003280.10 Reference assembly

    Range
    13820210..13820620
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_064489.1 → NP_496890.1  Histone H3 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_496890.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P08898, Q9TW44
    UniProtKB/TrEMBL
    K7ZUH9
    Conserved Domains (1) summary
    PTZ00018
    Location:1 → 136
    PTZ00018; histone H3; Provisional
Nucleotide Protein
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Gene LinkOut

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