U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ptr-19 SSD domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 191751, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
ptr-19
Official Full Name
SSD domain-containing protein
Primary source
WormBase:WBGene00004233
Locus tag
CELE_Y39A1B.2
See related
AllianceGenome:WB:WBGene00004233
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Involved in molting cycle. Predicted to be located in membrane. Predicted to be active in cytoplasmic vesicle membrane and plasma membrane. Is expressed in hypodermis; nervous system; and pharynx. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). [provided by Alliance of Genome Resources, Jan 2025]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See ptr-19 in Genome Data Viewer
Location:
chromosome: III
Exon count:
15
Sequence:
Chromosome: III; NC_003281.10 (10781853..10791176)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Condensin complex subunit 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C-type LECtin Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Kuwabara PE, et al. Genes Dev, 2000 Aug 1. PMID 10921907, Free PMC Article
  2. The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans. Zugasti O, et al. Genome Res, 2005 Oct. PMID 16204193, Free PMC Article
  3. Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions. Zárate-Potes A, et al. Front Microbiol, 2022. PMID 35620104, Free PMC Article
  4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in molting cycle, collagen and cuticulin-based cuticle IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in molting cycle, collagen and cuticulin-based cuticle IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasmic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
SSD domain-containing protein
NP_001255085.1
  • Confirmed by transcript evidence
NP_001255086.1
  • Confirmed by transcript evidence
NP_001255087.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10781853..10791176
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001268156.3 → NP_001255085.1  SSD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255085.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9XXR9
    Conserved Domains (1) summary
    cl25655
    Location:53 → 858
    Patched; Patched family

  2. NM_001268157.3 → NP_001255086.1  SSD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255086.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D2N110
    Conserved Domains (1) summary
    cl25655
    Location:53 → 680
    Patched; Patched family

  3. NM_001268158.3 → NP_001255087.1  SSD domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001255087.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    D2N109
    Conserved Domains (1) summary
    cl25655
    Location:53 → 674
    Patched; Patched family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools