Unc50 unc-50 inner nuclear membrane RNA binding protein [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Unc50provided by RGD
Official Full Name: unc-50 inner nuclear membrane RNA binding proteinprovided by RGD
Primary source: RGD:621749
See related: EnsemblRapid:ENSRNOG00000018128 AllianceGenome:RGD:621749
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Uncl
Summary: Enables RNA binding activity. Involved in protein localization to cell surface. Located in nuclear inner membrane. Orthologous to human UNC50 (unc-50 inner nuclear membrane RNA binding protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 168.9), Lung (RPKM 165.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 9q21

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	9	NC_086027.1 (47160723..47169710)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	9	NC_051344.1 (39664944..39674369)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	9	NC_005108.4 (44024994..44032896)

Chromosome 9 - NC_086027.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH142437 (e-PCR)
- UniSTS:231684

BI274353 (e-PCR)
- UniSTS:249064

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables RNA binding	IDA Inferred from Direct Assay more info	PubMed
enables RNA binding	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in protein localization to cell surface	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear inner membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: protein unc-50 homolog

Names: unc-50 homolog; unc-50 related protein (UNCL); uncoordinated-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.